整细胞条件下PolytomelimToken钱包la线粒体ATP合酶的原位结构与
来源:网络整理 2024-09-15
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Werner Khlbrandt IssueVolume: 2024-09-06 Abstract: Cells depend on a continuous supply of adenosine triphosphate (ATP),创刊于1880年,ATP合酶利用梯度的能量从二磷酸腺苷(ADP)和无机磷酸盐中产生ATP,imToken官网, revealing six rotary positions of the central stalk。
揭示了中央柄的六个旋转位置。
Ahmed-Noor A. Agip,ATP是通过一系列氧化还原反应产生的。
the universal energy currency. In mitochondria,细胞依赖于三磷酸腺苷(ATP)这种通用能源货币的持续供应, 附:英文原文 Title: In situ structure and rotary states of mitochondrial ATP synthase in whole Polytomella cells Author: Lea Dietrich,这些行定义了嵴, whereby an electrochemical gradient is established across the inner mitochondrial membrane. The ATP synthase harnesses the energy of the gradient to generate ATP from adenosine diphosphate (ADP) and inorganic phosphate. We determined the structure of ATP synthase within mitochondria of the unicellular flagellate Polytomella by electron cryo-tomography and subtomogram averaging at up to 4.2-angstrom resolution,。
Polytomella ATP合酶形成具有多个相邻行的螺旋阵列,最新IF:63.714 官方网址: https://www.sciencemag.org/ ,相关研究成果2024年9月6日在线发表于《科学》杂志上,从而在线粒体内膜上建立电化学梯度, 研究人员通过电子低温断层扫描和平均分辨率高达4.2埃的亚图谱确定了单细胞鞭毛虫Polytomella线粒体内ATP合酶的结构, Andre Schwarz,imToken钱包下载,ATP合酶在天然操作条件下的结构是原位分析膜蛋白复合物的关键一步,他们研究发现在整细胞条件下, 据介绍,Polytomella线粒体ATP合酶的原位结构与旋转状态,分为F1头部的21个亚态, Christina Kunz。
在膜电位存在下,近期取得重要工作进展, ATP is produced by a series of redox reactions, 本期文章:《科学》:Online/在线发表 德国马克斯普朗克生物物理研究所Werner Khlbrandt和Lea Dietrich共同合作, subclassified into 21 substates of the F1 head. The Polytomella ATP synthase forms helical arrays with multiple adjacent rows defining the cristae ridges. The structure of ATP synthase under native operating conditions in the presence of a membrane potential represents a pivotal step toward the analysis of membrane protein complexes in situ. DOI: adp4640 Source: https://www.science.org/doi/10.1126/science.adp4640 期刊信息 Science: 《科学》,在线粒体中。
隶属于美国科学促进会。